Literally meas "Mother Fucker". Typically expressed in a moment of dispair, impatience, disbelieve, etc. A parellel expresion and/or equivalent for "Chingada Madre" can be "Puta Madre".
1. Your girlfriend decides to give you some pussy and at the last minute she decides not to. With your eyes of disbelieve you stare at her and say "Chingada Madre".
2. You walk in a bus, look for change to pay the fare and find out you are short on change. Then you say "Chingada Madre". Be aware that most likely the bus driver will stare back at you in disbelieve and will also say "Chingada Madre".
by Yatej Odio April 30, 2008
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It’s like saying “muthafuka” or “ahh hell”
Usually used by Mexicans close to the border of Texas or Mexicans from the valleyDel Valle
1st person speaking to another, “ Your the One One who dropped it”.....2nd person’s reply “su madre guey
by Papí J August 14, 2017
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A Spanish expression translated litterally as "Oh mother!" but it have several meanings like Oh My God, Holy shit, oh crap, and anything that makes you look like WTF.
*F1 2010 German GP: La Sexta*

Smedley: "Ok.. so.. Fernando... is faster... than you... can you confirm you understood that message?"

Mark Gene: "..... Madre mia!!..."
by bullcrap December 5, 2010
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When Bobert’s mom goes crazy and beats the ever living shit out of him for staying on the PlayStation got too long or for doing something bobert would
Guys help me madre went madre mode
by Fabis March 21, 2020
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