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Hit the goose where it's loose 

1) To hit the nail on the head on an issue of some controversy, awkwardness or tension
2) To butcher one's words when saying something that could be controversial
3) Runny anal sex (like, liquid)
1) Gosh Tom, you really hit the goose where it's loose
2) Gosh Michael, you really hit the goose where it's loose
3) Alex, hit the goose where it's loose baby
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your dick's loose 

a not uncommon response to someone who talks a lot of bullshit or doesn't know what they're talking about at all, or someone of questionable sexual preference. also used to insult pretty much anyone at any time w/o any cause, mostly males.
Person A: That String Cheese Incident show rocked. They were throwin' down somethin' fierce.

Person B: Man, your dick's loose.
your dick's loose by Igz November 22, 2006

Jordan's loose butthole 

A hole that is very moist and loose on a man named Jordan. Aka VFT
This guy is so jordan's loose butthole .

what's loose?

What's up? What's going on?

Typically used as an actual question, rather than as a greeting (sup yo!)

Depending on tone of voice, may also be used in a state of anger, surprise or upset.
Frat 1: wohaa what's loose?!

Frat 2: You're mama's what's loose!

Frat 1: No I mean, what is going on here?!

Frat 2: Yeah, and I mean your mama's what's going on here!
what's loose? by vuck April 21, 2011

He’s Loose 

Grug “GASP” HE’S LEWSE (he’s loose) (steps on pointy rock and dies)
He’s Loose by Cenafan March 11, 2023

F's on the loose

A phrase used to describe a woman with huge hanging boobs.
Woman 1: Dude, did you see those F's on the loose?
Woman 2: Yea, they were huge.
Woman 1: It was like two watermelons were hanging from her chest.
Woman 2: But even with those things she was ugly as hell.
Woman 1: Yea, totally.

loose screw 

crazy; silly; mad; lunatic; loony; insane
"She's a little loose screw for talking like that to us."
loose screw by Pawnstar December 18, 2012