LIS simply stands for laughing in Silence. For all of you who have the addicting thing called myspace, use LIS instead of LOL.
Dude 1: That was fun shooting that video w/ AZN and Long Hair Man.

Dude 2: LIS, screw LOL
by Kirk Kaubish March 11, 2006
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Yo, I can't wait to go out to LI in the summertime.
by Harry Stotle January 19, 2008
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lies are like children- hard work! But in the end worth it because the future depends on them
man: hey stopping telling lies, thats bad!
child: actually you will find that they are the future, as am i
by Satan with a Perm June 22, 2010
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Hey I gotta go meet up with my li for date night, so I will talk to you later. All the best
by Rex Norman November 28, 2021
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Laughing inside. Polar opposite of LOL.
MK: "LOL"
MD:"that was actually an LI"
by MK JJ HB December 7, 2008
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Laughing Internally. Used when texting/chatting online and someone says something kinda funny but not funny enough to make you laugh out loud for real so you type LI instead!
Person #1: Hey, did you see that old man @ the store today??
Person #2: Yeah his pants were really up high. LI
by iwasbored September 1, 2010
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