It's the acronym of "Is Sana the Gayest?" featuring Japanese member Sana of the Asia One Top Girl Group "TWICE" who is infamous of being "gay" with her members.
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by Lester Englandson May 19, 2019
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An acronym. Usually used in texting that stands for "I Swear To God".
"Ugh, She is such a whore, ISTG." or "ISTG i hate you."
by Definition Maker #9812 September 16, 2018
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I was walking down the street this morning and istg i saw someone that looked exactly like you
by Truxkmayne September 13, 2018
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