Originally designed to discuss how IT is used to manage a business, Info Sys is by far the most piss-weak excuse for a subject! It struggles to express any logical information whatsoever; instead filling our minds with endless crap that is of no relevance to anyone! You become dumber for even studying it.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.