Homobo Share definition Flag One who is both a homosexual and a hobo One who looks like a homosexual hobo 1:Eyy did you see James today? 2:Oh, yeah man, he so looked like a homobo today. 1:RIGHT! Homobo by Mr.HoboKarma November 9, 2011 0 0 Get merch Get the Homobo mug. Buy Now — $32.95 See more merch