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The anal cavity; usually used when speaking in a sexual manner about taking it in the ass
Hey look at Adam, he is probably about ready to go down Misty's Hershey Highway again...
by Nilats April 25, 2003
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Nov 27 Word of the Day
A stupid person; it refers to the lack of surface area on an individual's brain. The general thought is that the more surface area (wrinkles, creases, etc.) a brain has, the smarter the person is. Conversely, a person with a smooth brain (no wrinkles) has less surface area and would therefore be stupid.
That fucking smooth brain put his shirt on backwards again...

That smooth brain is dumber than a pile of shit.
by Tip Tank May 14, 2011
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2
The reference of having sex with someones ass.
Bill-> I'd fuck her up the ass
Tyral -> I don't know man, there are not many chicks I would venture down the Hershey Highway with.
by Courchesne September 29, 2008
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3
brown eye; poop shoot; bung hole; shit slide; back door; asshole; cornhole; rectum; "exits only"
I'd fuck her again. She let me stick my willy in the hershey highway!
by Anonymous June 10, 2003
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4
There's a backup on Hershey Highway, I think it's a three turd pile up.
by AdamnJenn August 28, 2005
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5
Anal sex, however, it is mostly used to describe heterosexual anal sex, that is, penetration by the female in the anus.(HER-shey highway.)
She likes to take it up the hershey highway.
by Jonah Falcon October 11, 2004
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6
An expression for "taking the gay road."
"Why doesn't your son come with you to the games anymore?""Well, *sob* I'm afraid he has taken the hershey highway.
by running out of patience February 16, 2008
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