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Guard Dogs 

1: A girl's friends, who almost always make it uncomfortable to be around the girl you want to talk to. All girls have them, and they are a problem for most guys.

2: Dogs, usually Rottweilers or German Shepherds, used to guard prisons and other high security buildings.
"Hey, Terry, you should go talk to Maria"

"No way JT, she's got guard dogs like hell!"

"I'm almost out of jail! OH SH*T! I forgot about the guard dogs!"
Guard Dogs by Phenomenal1 April 20, 2010
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Guard Dogs 

One or several ugly women that seem to hang around attractive females, offering protection and an effective deterrent against hopeful males.
"Hey dude look at that hottie over there?"

"No chance mate you have to get past the guard dogs first!"
Guard Dogs by Alex Tooth May 8, 2008