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Guano Loco 

Batshit Insane.

Crazy, in fact probably totally insane.

Acting in the manner of Tom Cruise jumping on Oprah's sofa or Joaquin Phoenix on the Letterman show.

Hearing voices and imagining things that haven't happened or people saying things that they haven't.

Possibly caused by some recent trauma, however more than likely always present just brought to the surface in times of high emotion.
Person 1: "What's up with that girl talking to herself?"
Person 2: "She's been totally Guano Loco since her boyfriend moved to Greece and dumped her ass"
Guano Loco by Bush Girl September 4, 2009
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guano loco 

almost all politicians are guano loco
guano loco by J.Richard January 7, 2008

guano loco 

Neil Halelamien is guano loco, man!
guano loco by tagonist July 16, 2009

Guanoloco 

Using Spanglish to be politically correct when there is crazy ass shit going on all around you that blows your fucking mind.
Drinking a stranger’s tequila and then sharing their toilet to puke in with your underage Latino brother, while your 5 children throw gumballs in their fish tank is guanoloco.

Crashing a BBQ at your ex-boyfriend’s brother’s house then telling your 4-year old to piss in the bushes and pretend he is camping is guanoloco.
Guanoloco by astipup May 5, 2018
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