The act of consuming LSD a few hrs after consuming LSD.
LSD dose dose up
by festival loiterer March 1, 2012
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Asking someone to shut up (be quiet); Saying that someone needs to shut their mouth; Wanting to shut someone up; Wanting someone to just shut the hell up already.
"Dude, someone really needs to make Jeff swallow a big ol' dose of shut up."

"Sarah... damn girl, you need to swallow a big dose of shut up before something bad happens to ya."

"Man... someone needs to make him swallow a big ol' dose of shut up already!!"

by LadyDucatnip May 1, 2008
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A derogatory term used by incels to call someone crazy for having a different opinion.

To dose up means to take larger doses of medication, or to go on medication, therefore implying the person that should dose up has a mental illness.
Guy: "I don't like the band Deftones."

Incel:"Dose up kid they're the best."
by holyreturn October 2, 2022
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