derpus- grande Share definition Flag Largest possible quantity of derpness known to mankind. One who acts in derpus manner of extreme magnitude. Id say that manuever was derpus- grande; your lucky to be alive! derpus- grande by Larry Goldsmitz December 26, 2007 0 0 Get merch Get the derpus- grande mug. Buy Now — $32.95 See more merch
