A substitute for "God bless you."
You know...when you sneeze.
Little Girl: Aaa..aaa...aaachooooooooooo!
Grandma Blessy: BLESSYKINS! BLESSYKINS!
by Farzad October 9, 2005
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a high pitched optimistic response to a sneeze, usually uttered by someone over the age of 97
bobby: i think im about to sneeze....

grandma: BLESSYKINS IN ADVANCE!!!!!
by levyyyy November 28, 2005
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