An obscure illness, disease or condition affecting a comparatively small number of people, but with symptoms somewhat similar to one or more different and more common illnesses.

It is named because these diseases/conditions are sometimes misdiagnosed by well meaning (but often inexperienced) doctors when something far more common is actually the cause. Medical students are told "remember, if you hear hoof beats, think horses, not zebras".
Doctor 1 - "I think this patient may have Castleman's disease"
Doctor 2 - "Castleman's disease is a zebra, there are far more likely causes of his fever and weight loss."
by PiemasterUK December 8, 2010
Get the Zebra mug.
Zebra is a woman who is free spirited and can not be tamed. They can be the most loving that you will ever meet but if you attemt to put a saddle on them they will run away
So im dating this girl....I really like her but im taking it slow because shes a zebra
by BIGGDAD September 13, 2009
Get the Zebra mug.
When a chick was fat, she slims down
Leaving Stretch marks... reminding of Zebras stripes
That Girl is a Zebra...
by Kriix April 16, 2009
Get the Zebra mug.
The Chief can be a real zebra sometimes
by Stitch2002 December 5, 2018
Get the Zebra mug.
THE most legit animal on planet Earth, Mars, and Jupiter.
Holy shit, did you see that zebra? Hella legit!
by babbbbaay13 January 5, 2010
Get the Zebra mug.
Ze Garment zat covers ze boosom
Phil: check out Zebra on sale!
Bill: Zat is sweet
by Ryan J Johnson August 28, 2005
Get the Zebra mug.
When you are having sex doggie-style with a black girl, and you cum on her back in stripes, making her look like a zebra.
Hey Steve guess what!" "What?" "I just zebra'd on Rhianna.
by mrfairyuniverse July 25, 2011
Get the Zebra mug.