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Your Sister a Mister

Only used by the almighty, worse then your mom gay and everything else
Caleb:Your mom gay
Kyle:Your dad a lesbian

Caleb:Your granny tranny
Kyle:Your gramp tramp
Caleb:I'm sorry but you have insulted my to my boiling point and now I'm afraid I have to use a forbidden phrase upon you
Kyle:Do it pussy
Caleb:Your sister a mister
Kyle:Just fucking melts

your sister a mister

only used as a last resort once your homeboy hits you with to many no u this cannot be countered until we find the holy trinity
carl: your mom gay

me:daddy tranny

carl:no u
me:your sister a mister

carl ;evaporates

your sister a mister

your sister a mister is possibly the worst insult ever created. It will destroy an entire dimension whenever it is used. Another language had to be made to create this phrase, and this is the rough translation. Calling someone's sibling trans is easily worse than Your mom gay, Your dad lesbian, Your granny tranny and Ur grandpap a trap are hardly insults copared to your sister a mister.
God: Are you a little bitch?
Me: Your sister a mister
God: *Fucking dies on the spot

your sister a mister

worse than your mom gay your dad lesbian and your granny tranny
fred:your mom gay
joe: rour dad lesbian
steve: your granny tranny
brandon trembling from all the bad insults: your sister a mister
fred, joe and steve all explode

Your sister a mister

Dave: Your mom gay
Dan: Your dad lesbian
*Dave dies inside*
Dave: don't make me do this
Dan: try me bitch
Dave: your granny tranny
*Dan explodes*
*Dan's ghost comes back*
Dan's ghost: Your sister a mister
*The entire universe collapses and everybody dies*
Your sister a mister by Pronas March 12, 2018

your sister a mister lol 

One of the more gritty underground roasts, please use with extreme caution. May cause recipient to go into an anaphylactic shock, epileptic fit and or straight up seizure. Other side effects which have been known to be a consequence of this insult includes full-blown autism or an addition of a chromosome.
Sarah: Your mother is a child-beating, cheap whorewho has achieved nothing manage to trap a man to have a child with her, a massive mistake... you. That mistake is you, you unloved virgin.

Janet: your sister a mister lol

Sarah: *Develops autism and literally fucking dies from her throat closing up*

Your Sister is a Mister 

The ultimate comeback that were Steven Hawking’s final blessings to us before his passing.
Steven: Your sister is a mister... *final breath*

Man: What an OG that man was
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Example 2:
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