Tittyskittles 

A slang term amongst Male to Female transsexuals for Estrogen pills.

I've been on tittyskittles for 3 weeks...

Tittyskittles by abbiistabbii March 12, 2010

Titty skittles 

A word used by trans girls referring to the pills that they usually take in their transition. It's mostly used as a meme.

Titty skittles is good and all but what about anti-cistamines?

Titty skittles by Cosmonaut_Luna June 4, 2019

Titty Skittles 

Another word used for trans women going on HRT. They usually refer to oestrogen pills.

So I've heard Amie is getting titty skittles soon!
Yup, she is getting them soon. She's finally going to go on and become the woman she's always been.

Titty Skittles by SpookjeEmily August 26, 2019

titty skittles 

hormone pills to grow (larger) breasts, sometimes used by mtf transexuals

titty skittles do not taste like the rainbow

titty skittles by p00per September 8, 2010