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The Stuff 

1) The most bizarre film of the 80's by Larry Cohen. With is three-color appealing packaging, the American public start to devour the dessert in a maniac fashion. An industrial espinonage expert soon relalise that the Stuff is an living organism that take over the brain of those who eat it, turning them into zombie creature.
2) the best crappy horror movie ever!
Hey, that movie "the Stuff" that you suggested kick ass!
The Stuff by Lydia Bergeron March 31, 2003

the stuff 

slang term to describe AIDS
Watch out for Wayne cause he has the stuff.
the stuff by Johnny Tats January 12, 2008

the stuff 

Premier term referring to drugs, especially marijuana.
"Uh thanks but I don't need....the stuff."
-me after being asked, "hey Dave wanna smoke a bowl". This is pretty much my answer whenever I'm asked that. lol
the stuff by Dave February 22, 2004

the stuff 

That special something which allows a person to perform at the highest level.
Or
The actions themselves which require that special something to perform at a desirable level.
"We've got to sign this kid to a contract, he's got the stuff."

"The artist has refined their techniques and style through their years but it is clear even from their early works that they always had the stuff."
the stuff by Andrew Mil May 30, 2021

the stuff with the what not 

A technical term used excessively at Autozone to describe automotive parts in excruciating detail.
Customer : Hey, I need a part for my car that has this thing that comes off from the side and kinda wraps around like a "u" shape. You know...?

Autozoner : Yeah, kinda like the stuff with the what not, on the thing with the part on it... I have one in the back.

That One Guy With the Stuff 

He's that one guy that you know, and that everyone else knows, but you don't know his name. You do know that he's that guy, not the other guy, but that one guy, you know, the one with the stuff in the thing. He also has some hair and that one thing where he goes places a lot of the time sometimes.
Tyler: Do you have the notes?
Zane: No, that one guy does.
Tyler: Which guy?
Zane: You know, that one guy with the stuff, and he has that thing with the stuff in it, not the other guy, the one who has that thing where he goes places. Do you know who I'm talking about?
Tyler: Yeah, you mean that one guy with the thing where he has hair and stuff right? I know who it is, thanks.