sucked up Share definition Flag The look of a tweeker after prolonged use of methamphetamine, such as sunken cheeks, pale, malnourished, heavily fatigued, etc. Man that tweeker was looking sucked up when they booked him last night. sucked up by moth17 May 26, 2006 0 0 Get merch Get the sucked up mug. Buy Now — $32.95 See more merch