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A great good looking guy, sometimes cocky-er than should be and an unusually large penis. Highly intelligent and educated. Acts sometimes like he doesn't care but deep inside he is very cuddly like a teddy bear. Ever guy wishes he was Santo. Also a sexy guy that liked the women and has a nice tooth brush

Boyfriend: OMG there's Santo, I wish I was like him.
Girlfriend: Sigh....I wish you were like him too.
Santo by Definitions0098008 February 4, 2010
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Virgin Island term for Dominicans, mostly because of the capital city of the Dominican Republic is Santo Domingo and such a large influx of Dominicans live,in the Virgin Islands.
Utah:I tought she wuz a Puertorican!
Kathleen: No, she a Santo
Santo by Damiien October 17, 2007
An extermely handsome man that is atheletic. All girls die over Santo. A Santo can get the hottest girls and keep them because he knows how to treat them. If you have an chance to date a Santo do it there wont be another like him. Santos are rich, and always knows how to be slick about things.
Is that a santo right their? Hes looking cute.
Santo by BigCripper69 April 24, 2019
A man with a fucked up mind. He goes around saying anything that comes to mind, no matter how reatrded or disbelievable it may sound.
Santo: "What if that lolipop you were eating somehow came alive and started screaming in your mouth with a bloodcurtling scream 'help it hurts'?"

Everyone else: "Dude what the fuck????"
santo by Doofniggah October 14, 2011
A middle aged guy who gets divorced and dates women half his age, usually while acting like a saint.
Dave has turned into a total Santo. He asked out his daughters friend on Facebook
Santo by Margaritamayhem March 23, 2022
A guy who'll jump into danger for women but wouldn't even move if his guy friends were on fire
Adi: He would rather die for a random girl than help me move out.
Giffee:Don't bother man. He's such a Santo!
Santo by ad411 October 10, 2019