S.T.D.licious Share definition Flag Someone who's absolutely beautiful, but a total slut/manwhore. Irresistable, and possibly infectious. "Oh, god, look at her!" "I know her--slept with Cincinatti." "Maybe, but man... S.T.D.licious" S.T.D.licious by Tiggums October 17, 2008 0 0 Get merch Get the S.T.D.licious mug. Buy Now — $32.95 See more merch