A large quanity of digital hued squares are quite sexy when they are in groups of many, like my mate on Furcadia, Zilanthia having the finest pixels around.
A meme within the SCP fandom referring to a containment breach of SCP-096 that was caused by "four Pixels... Four Fucking Pixels" the photo was taken by a civilian on a mountain and the breach was caused by the same civilian
Sometimes a LCD / TFT monitor will have one or more pixels that are not working. These will remain a certain color or be black or white, but won't display colors dinamically like the rest of the screen. There's nothing you can do about them yourself, but normally manufacturers will give you a refund.