An abbreviation for mystical.
"It's phony, goddamn it but mysto and after a while it starts to infect you, like an itch, the roseola." p.19 of The Electric Kool-Aid Acid Test, by Tom Wolfe.
by ASlateReader August 23, 2011

Ted has gone mysto on us ever since he started coaching his kids. Hope he pops up for a beer some day.
by selgreco May 18, 2018

An abbreviation for "mystical."
It was mysto why there wasn't a definition on Urban Dictionary for "mysto," so I made one, immediately after some dumbass on Slate said there wasn't one, rather than just making one himself.
by Kenboy August 23, 2011

An abbreviation for 'mystical'. Coined back in the sixties when any experience with drugs were considered mystical.
by Kidnap The DJ August 22, 2011

by Bill from RNOC August 23, 2011

Mysto is an anime tiktoker his favorite anime is dbz he never misses and he usually comments W or L on posts he sees.
by Flip900 March 17, 2021
