Meserole Share definition Flag An extremely crazy, loud, drunk, large, group of family that shows affection by making fun of and/or fighting with eachother. Holy shit they are loud! Oh, they're just meseroles. Meserole by Aye, Bernadette. August 7, 2008 0 0 Get merch Get the Meserole mug. Buy Now — $32.95 See more merch