A term used on 4chan's /lgbt/ board used to refer to masochistic emasculation fetishists, or men who take pleasure in being humiliated by being feminized. See sissy fetishists.
Even though Alice was insecure about her hairline, she refused to wear a wig as she did not want to be confused for an MEF.
by fullbodyphallo October 1, 2022
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Mother Everyone's Fucked. Derived from the example of MILF as noted in the classic movie, "American Pie". This term is used for a female who use to be a slut, but then settles down, gets married and has a kid.
"Damn, I ran into Jen today and found out that she's married and had a baby. You remember Jen don't you?? What a MEF!"
by KiKKi January 14, 2006
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Mortal Enemy Forever. The opposite of BFF
He was once my BFF, but then he committed a grevious crime and became my MEF
by DoomLord June 26, 2009
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"Yo Mef wheres my killa teeth at?"

Dirty Mef (421 the Day After...)

by Jeff Jang October 25, 2006
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Meffed is a combination of the words messed and fucked up
Yo go check ya friend he seems a lil meffed up
by Sam A. January 22, 2006
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mef-derived from the insult meffa or indeed mephloid.
Someone of limited inteligence/extreme clumsyness.
or indeed someone whose limited spacial awareness and general geekiness makes them satnd out from the crowd of geeks
by FITZNICENTIGHTLY October 14, 2004
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