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lose one's cool 

Not staying cool and in control. The opposite is to keep one's cool.
Don't lose your cool, man!

One will fail if one lose one's cool.

lose one's shit 

To have a complete mental and physical breakdown as a result of someone's jackassery or assholery.
When I mentioned I wanted to become a woman, my girlfriend totally lost her shit.

Good grief, if you kids don't stop with this jackassery, I'm going to lose my shit!
lose one's shit by groovygrrl October 13, 2004

Lose one's ass 

Do so bad that you lose even what's impossible to lose, your ass.

In the Old West people used to bet their ass (donkey) in gambling and lose it, so that’s where this saying started.
We lost our ass on that game.

If this presentation doesn't go well I'll lose my ass!

To lose one's ass is to lose all.
Lose one's ass by kloon882 April 28, 2019

to lose one's touch

To lose the ability or talent once had. No longer being in posses of a particular skill or a set of skills towards a certain matter.
Pietro is no longer able to present classes, he has completely lost his touch.

NOTE: to lose one's touch was applied with "his", could be her, its, your, our and their.
to lose one's touch by teachergui January 17, 2018

Lose one's shit 

Verb. To become so overwhelmed with excitement or euphoria that a person literally shits themselves, often without realising or caring.
To lose one's shit:

"You should have seen him - he was so happy with the result that he lost his shit!"

"Her crush made eye contact with her and smiled, and she lost her shit."
Lose one's shit by Sakura44 June 20, 2016

Lose one's shit 

To lose control of one's behaviour, to the point of verbal and/or physical aggression.
We've had to deal with quarantine protocols for a week and all residents have had to remain in their suites with no visitors. Some of the residents that have more advanced Dementia are losing their shit. They're becoming physically aggressive. But to lose one's shit comes more easily with quarantine than one would otherwise think
Lose one's shit by chrisssy226 October 25, 2020