1 definition by Sakura44

Verb. To become so overwhelmed with excitement or euphoria that a person literally shits themselves, often without realising or caring.
To lose one's shit:

"You should have seen him - he was so happy with the result that he lost his shit!"

"Her crush made eye contact with her and smiled, and she lost her shit."
by Sakura44 April 7, 2016
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