James Guo Share definition Flag A small little boy that has no sense of direction. Usually hopeless in every romantic situation. Everyone hates him except himself Wow im a James GuoYour such a James Guo!Is that a James Guo? James Guo by ArMach January 7, 2019 0 0 Get merch Get the James Guo mug. Buy Now — $32.95 See more merch