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Leftover dense material. Used to describe industrial sludge. Another informal usage refers to the last few centimetres of coffee at the bottom of the pot.
I don't have another time to brew a fresh pot. So I'll just nuke yesterday's dregs.
Dregs by radiosonde1 July 30, 2009
Although it most commonly refers to the beer at the tail-end of a beer, it can also refer to someone's leftovers, or sloppy seconds. This also applies to sexual 'sloppy-seconds' by which it refers to someone that the subject has already had sexual intercourse with.
Dude, like I know you think she's hot, but you'd be doing Dan's sloppy seconds... It's his dregs man! HIS DREGS!
Dregs by FLAMES! May 1, 2006
1. A rare, unique slang meaning "the worst part(s)" or "dirty/grimey".
2. "Fuck."

The word's original origin comes from wine brewers. "Dregs" or "lees" were the words applied to the wine residue during the aging process. "Dregs" also comes from the grammatical base of the word "dark".
1. "The best deals are in the dregs of the city..."

2. Tanto: "Shoot 'im! Shoot 'im!"
*won't fire*
Tanto: "It's on safety!"
Garie: "DREGS!!"
dregs by nikkan_hanil September 23, 2004
The reusable residue left after cooking an opiate for the purpose of injection.
I'm dopesick enough that even your dregs are enough to get me off.
dregs by Greg A. June 25, 2005
Somtimes referred to as a hangover, or many days not taking a bath and you look like skidrow, or a bad hair day.
>
Gina: "Man the dregs are beating you down. You need to drink less"

John: "Hey, get off my case. I'll drink all I want!"

>
Chris: "Man your dregs stink. Clean your act up! You look like skid-row!"

Mark: "Man I don't feel like it."
dregs by JamBot October 16, 2006
The last mouthfuls left in a bottle of an alcoholic substance.
“Ah he left me with the dregs.” -Sara
dregs by Sandra D.S. January 13, 2023