DFM

Disease fucking modifying

Hey, Adrian said this drug was just a placebo and that's why patients improved 18 months from baseline. Is it true?

No, that bald overweight guy with a cheap ass suit doesn't know shit. That drug is DFM, which is why the patients are improving

by Garp.has.smol.PP October 27, 2023

DFM

Dance-floor makeout.

Do you even remember your DFM from last night? He was so hot!

by n8a March 20, 2010

DFM

An expression of indifference and disassociation capable of being used in almost all contexts. Exceptionally useful to dispense with ones own cock ups and your own or another's dissapointments. "Doesn't Fucking Matter"

George passes out paraletic on the couch and while he snores he pisses in his pants. On waking he realises his wife will discover his embarresing moment and sighs,"DFM".

Ollie fights for hours to land a Roland Ward marlin and in the death throws of the epic fishing battle George bumps his rod, the line snaps and the enormous fish escapes. George, to appease his concience, to hide his shame and to lighten Ollie's dissapointment exclains:- "DFM".

by DFM January 08, 2008

DFM

Deep Fried Memes

Just got done scavenging the Discord server for some crispy DFM

by TheFudgeBro October 25, 2018

DFM

Don't follow me.

Little pervs and old wierdos DFM on twitter.

by KiwiSayWhaaat?? June 19, 2009

DFM

Displays of fragile masculinity

DID You catch that DFM? Kevin just told me he works out 10 hours a day.

by hailkev November 29, 2017

DFM

A woman with physical and mental disabilities who likes to blame society and not her own failings as a person for all that is wrong with her life.
Commonly spotted in amongst free cheese lines at major welfare hand out shelters.

Did you do a DFM today?
No, I worked for my cheese today.

by popular girls November 20, 2003