dab me up means to put yellow thc oil/wax/shatter/dab into a smoking or vaping mechanism in order to get medicated or high. Sometimes confused with dap / dap me up , which is actually an unspoken greeting by fist pounding but is different then the game of bloody knuckles.
If you ever go to composite high school in Fort McMurray and someone comes up to you and says dab me up bro you high-five them with you handparallel thumbs up then fist bump