Butt Herp Share definition Flag Manifestation of the herpes simplex virus on or around the anal sphincter. Jesse passed out in the bar last night in Cancoon. He woke up in some dude's trailer naked and well, he's probably got the Butt Herp now. Butt Herp by tacospank April 6, 2011 0 0 Get merch Get the Butt Herp mug. Buy Now — $32.95 See more merch