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321 by mellissaa November 13, 2006
Related Words
countdown county
The area code for most of Brevard county, Florida: includes the Kennedy Space Center
unites the G's of Cocoa and Palm Bay and the Surfers of Beachside and the gayass emo bitches of Cuntree.
bitch, tha 321 got that funky krip nugs.
321 by abeck March 1, 2008
used in the game of beer pong when there is only six cups left and the person wants them in a 3-2-1 set up, like a beeramid.
321 by holi64 June 23, 2008
When you disagree with someone or something, usually used on the internet.

This derived from chat rooms when people would typically ask you type in 123 if you agree with someone. For example "Press 123 if you like _______." People who would disagree would type the number backwards. It is not necessary to say you disagree, as it's a subtle enough sign of saying that you don't.
Jessica: "Press 123 if you're looking forward to the concert!"
David: "321"

John: "So who likes Dubstep and Rock mixed together?"
Jake: "321"
321 by Omega Royale March 25, 2013
n. Used to describe someone who is retarded, moronic, stupid, inept, etc.
Derived from the disorder Trisomy 21, which is the cause for down syndrome. A handy phrase to use in public when you want to call something retarded, but the non-politically correct nature of the word doesn't allow you to do so.
Person 1: "Did you hear that Robbie failed all of his classes?"
Person 2: "Wow, what a fucking 321"
Person 1: "Such a 321... after I told him I failed one, he was like 'That's NOTHING, I failed ALL of mine.'"
321 by Snackrabbit December 2, 2009
An insult similar to "fucken retard"
three-twentyone is the genetic code for Down Syndrome, a genetic disorder, a common form of retardation
"He was devastated when my friend called him a 321"
"Yes, ma'am, i'm sorry, but your child is a 321"
321 by puffyquail March 5, 2019