The Florida area code for Kennedy Space Center, Cape Canaveral, Cocoa Beach, and nearby areas. Coincidently it also represents the last three seconds of a space launch countdown. Making it very easy to remember.
I live in the 321 area code.
by 321 October 26, 2006
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countdown county
The area code for most of Brevard county, Florida: includes the Kennedy Space Center
unites the G's of Cocoa and Palm Bay and the Surfers of Beachside and the gayass emo bitches of Cuntree.
bitch, tha 321 got that funky krip nugs.
by abeck March 1, 2008
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used in the game of beer pong when there is only six cups left and the person wants them in a 3-2-1 set up, like a beeramid.
by holi64 July 11, 2008
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When you disagree with someone or something, usually used on the internet.

This derived from chat rooms when people would typically ask you type in 123 if you agree with someone. For example "Press 123 if you like _______." People who would disagree would type the number backwards. It is not necessary to say you disagree, as it's a subtle enough sign of saying that you don't.
Jessica: "Press 123 if you're looking forward to the concert!"
David: "321"

John: "So who likes Dubstep and Rock mixed together?"
Jake: "321"
by Omega Royale March 26, 2013
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n. Used to describe someone who is retarded, moronic, stupid, inept, etc.
Derived from the disorder Trisomy 21, which is the cause for down syndrome. A handy phrase to use in public when you want to call something retarded, but the non-politically correct nature of the word doesn't allow you to do so.
Person 1: "Did you hear that Robbie failed all of his classes?"
Person 2: "Wow, what a fucking 321"
Person 1: "Such a 321... after I told him I failed one, he was like 'That's NOTHING, I failed ALL of mine.'"
by Snackrabbit December 3, 2009
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An insult similar to "fucken retard"
three-twentyone is the genetic code for Down Syndrome, a genetic disorder, a common form of retardation
"He was devastated when my friend called him a 321"
"Yes, ma'am, i'm sorry, but your child is a 321"
by puffyquail March 6, 2019
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