Short for "too edgy for me", a phrase commonly used in response to something obnoxious, irritable or cringe-worthy. It is also an effective general-purpose criticism that requires no effort on the maker's behalf.
Values can be also added onto the 2 and 4 for variety/emphasis, e.g. 3edgy5me.
A: Hey faggots, My name is John and I hate every single one of you.
B: 2edgy4me
A: jus wrote nigger in a handicaped toilet stall #fukdapolice #thuglyf
B: 6edgy11me
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.