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one eyeing it 

When someone is so drunk they shut one eye, leaving the other eye to focus in on what theyre doing.
P: how much has jim had to drink?

Eric: 3 Cocaine in the Veins..why?

P: watch him text..hes one eyeing it
one eyeing it by Perrotta December 17, 2008

one-twenty-oner 

Anyone that was of the opinion that everything was OK with the US under the unrepentant Bush administration, but suddenly the day after Obama's inauguration (1-21) government was too big, taxes too high and all was wrong with the government.
Rush Limbaugh and Republicans supporting Bush and his cronies and exhorting us to blindly support "The President" but now blame President Obama for all of the country's ills and want him to fail. Classic one-twenty-oner mentality.
one-twenty-oner by Bat Guano May 10, 2009

one handed phone call

A phone call made whilst masturbating.
Pat O'Brien is a big fan of making one handed phone calls.

One Eyed Wizard 

1. A name for the male reproductive organs
2. A name for a special type of device for consuming cannabis
Hey man, last night I was hitting the one eyed wizard.

I think that's a penis.

No man, a device used for recreationally smoking Mary Jane.

Oh OK.

One Shitter Quitter 

a short, quick dump that requires only one wipe to ensure cleanliness.
Pat: we're leaving in 5.

Rob: dude, i've gotta shit.

Pat: you better make it a One Shitter Quitter then.

One (singular sensation) 

A secret code used among theatre kids, especially in gym class. It is used as a method for detecting and recognizing fellow musical lovers.
Gym Teacher: I'm going to count off by fours. All the ones go stand to the right."

Theatre kid #1: "One..."
Theatre kid #2: "...singular sensation!!!!!!!"
Theatre kid #1: "Thank God, someone who understands me!"
Theatre kid #2: "One (singular sensation) never fails."