An anime originated term used to describe when a female side character with more character development than a main female character whom both show affection/ love interest to a main lead (usually male). The side character ends up building a lot of attention and cheering for her and her interest. The effect ends with the side character having her feelings rejected by the Main lead.
"Hey dude, what did you think of Ana? I hope she ends up with Taichi and isn't shut down by the Rem Effect."
by Aura babyy August 14, 2019

The knowledge of impending doom caused by the conclusion of the Mayan calendar and feeling like everything is going to be fine.
Jack: It's the end of the world as we know it. And I feel fine.
Jim: He's suffering from REM Syndrome
Jim: He's suffering from REM Syndrome
by waynelouis December 21, 2012

by asdasdasdadwasdw December 13, 2020

by Yunko December 10, 2020

Latin for "go to the bad place", which translates as "go to hell". The Romans considered it unlucky to name the bad place.
by moonbug November 17, 2006

by Natahan1996 June 30, 2021
