Duff

Duff is an acronym meaning Dumb Ugly Fat Friend or Designated Ugly Fat Friend.

Generally a cockblocker and a bitch, have a desperate friend take her down.

Friend 1: Dude I want to hook up with that girl, but her duff is in my way.

Friend 2: It may be Amber but i'll take the duff down.

by Jap Anus Relations July 29, 2009

DUFF

Designated Ugly Fat Friend

Wow, who brought the Duff to the party!?!? Not cool guys...

by DUFF HUNTER August 15, 2009

Duff

the ugliest friend in a group to make everyone else look better.

Wow, elliot is the duff in that group.

by mobojobo February 2, 2015

druff

Street term for visble dandruff on the scalp and shoulders.

Man, you've got a bad case of the druff.

by Kristobel August 28, 2006

Leetish Duff

A 12 year old boy on minecraft that brags about having sexual intercourse girls on minecraft, Has a massive ego and claims to have a massive willy but is actually 12. Uses cringe pickup lines and has the body and face of an 8 year old. Definition of a horny 12 year old.

Leetish Duff: I've dated many girls and i have a massive pp, i've had intercourse with multiple people on minecraft and im 12.
Girl: Yes please Duff Daddy, i love you please date me!

by Anonemoss June 2, 2017

dufflebag

n. Something used to carry around your useless shit or defication. Usually worn by the Cha-Chas.

I saw Cha-Cha with his pink dufflebag yesterday, what a hottie.

by Jennifer May 13, 2004

duff

faulty, sub-standard

by doof April 23, 2003