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Duffsex is where erectile dysfunction, performance anxiety or alcohol intoxication leads to the disappointing premature discontinuation of intercourse without climax by either participant.
guy1: dude, did u hear hadi got laid last night? with this bear fit irish chick innit!
guy2: yea but it was duffsex... how embarrasing. shame about the bird too, she's zhaofit.
guy1: no way! is he gay?
guy2: no think he was just too wasted innit and such.
guy1: well, at least he didn't have to pay this time.
Duffsex by chairmanzhao May 31, 2010
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Leche duffles 

A term to describe really nice, big, voluminous boobs.
Wow look at her leche duffles bro!
Leche duffles by Disos October 2, 2021
To get Your shit rocked by a closed fist.
Yo Son just got the shit duffed outta Him.
Duffed by Moe June 18, 2006

Duffers' Syndrome 

A slang term for the very serious medical condition duphershypertrophy whereby the sufferer acquires over time excessive fatty tissues to the nasal region, giving the patient the not unpleasant features of a gnomish looking fellow; rosy cheeks from the strain of holding one's nose up all day, at times somewhat gormless facial expressions (which can be attributed to the drag-factor but more often can lead an innocent bystander unaware of the condition to conclude that the sufferer is possibly some sort of simpleton) and of course the ever-expanding, bulbous nose which grows and grows like in that fable about the enormous turnip...

Prognosis: Not good; rhinoplasty recommended.
What are you doing resting your nose on that snooker cue? Have you got Duffers' Syndrome or something?
Duffers' Syndrome by Mouldy123 April 3, 2011
to duffet: (duf-it) to screw someone out of their money, in snakey type manner. To not pay money to someone that you owe monetarily. To get work out of someone without paying them.

*The people getting screwed are of no significance even if family or friends.
fuck me. I worked with that motherfucker for a week and he duffeted me out of $300. Never gonna work for that cheap douchebag again -_-
duffet by garbanCHIC May 4, 2008

New Jersey duffelbag 

A very large, gaping, and over-used vagina.
"So Les, did you ever poke that Shirley chick?"

"Of course I did... Me and the whole football, basketball, hockey, baseball, and soccer team. That girl's got quite the new jersey duffelbag!"
To get your ass kicked REALLY badly. If you got "duffed", you didn't just get punched in the face, hit the floor and kicked once or twice hard... you got hit in the face, hit the ground, then got hit in the face several more times, possibly had your head bashed into the cement, got kicked in the ears, neck, kidneys and various other soft spots on your body.
"Yung, that nigga D-Set laid up in the hospital. He smoked up that whole QP he was fronted by main man and got duffed."
Duffed by Krill Awareness April 15, 2006