2-Iodothiophene (TP-I, Thiopheyl iodide, 2-ThioPhenyl iodide) is used as an intermediate in the synthesis of TP2P (ThioPhenyl-2-Propanone, 2-Thienylacetone). 2-Iodothiophene can react with ethyl acetoacetate and sodium ethoxide using CuI (Copper Iodide) and then reacted with hydrochloric acid and heated. 2-Iodothiophene can also undergo grignard reactions to obtain TP2Pol (ThioPhenyl-2-Propanonl, 2-Thienylisopropanol).
2-Iodothiophene has been obtained by addition of half of 50% aqueous nitric acid dropwise to a mixture of iodine and thiophene with vigorous stirring. As soon as the evolution of gases subsided the rest of the aqueous nitric acid was added to the reaction mixture and refluxed for 30 min. The organic layer was separated and steam distilled to obtain 2-iodothiophene.
Iodination of thiophene with iodine and mercuric oxide at 0°C gave a mixture of 2-iodothiophene (70%) and 2,5-diiodothiophene. 2-Iodothiophene has been exclusively obtained by nitrating thiophene with a mixture of iodine and nitric acid at 90°C. An easy approach for iodination of thiophene is the reaction of iodine with lithiated thiophene.
2-Iodothiophene has been obtained by addition of half of 50% aqueous nitric acid dropwise to a mixture of iodine and thiophene with vigorous stirring. As soon as the evolution of gases subsided the rest of the aqueous nitric acid was added to the reaction mixture and refluxed for 30 min. The organic layer was separated and steam distilled to obtain 2-iodothiophene.
Iodination of thiophene with iodine and mercuric oxide at 0°C gave a mixture of 2-iodothiophene (70%) and 2,5-diiodothiophene. 2-Iodothiophene has been exclusively obtained by nitrating thiophene with a mixture of iodine and nitric acid at 90°C. An easy approach for iodination of thiophene is the reaction of iodine with lithiated thiophene.
Tony: I iodinated thiophene using nitric acid and slowly added it, then refluxed it for 30 minutes at 90 °C. I obtained 2-Iodothiophene.
by CognitiveFuel September 12, 2023
The equation of choice among math paradoxers and recreational mathematicians, who unspokenly derive much satisfaction in exposing students’ fallacious or illogical reasoning that leads to the contradictory result.
Be it due to division by zero or squaring (or square rooting) both sides of an equation, few students wouldn’t want to know why “1 = 2” is logically plausible.
by Fasters May 03, 2022
Kid:Hey grandma
Grandma: Hey
Kid: It’s Nov 2 which also means it’s national throw it back with you me grandma day
Grandma: *Throws it back*
Grandma: Hey
Kid: It’s Nov 2 which also means it’s national throw it back with you me grandma day
Grandma: *Throws it back*
by KSIWONFUCKLOGANPAUL November 10, 2019
January 14th, 2073:
"Dad what is part 2?"
"Legend says it was meant to be the 8th world wonder, son."
"Dad what is part 2?"
"Legend says it was meant to be the 8th world wonder, son."
by Ficpart2 January 14, 2020
skanky girl who wears booty shorts and bebe shirts also cant get into the club so she stays out side
by ass in the hole June 28, 2016
When you and your lover order the 2 for $20 deal at Chili's, and fuck in the bathroom while you wait for the food to arrive. Return to the table, eat the meal, and fuck again while you wait for dessert.
License to grill!
License to grill!
Chili's is offering the 2 for $20 again, so Ashley and I got the steak, the lava cake, and double oral all for $20!
Whatta deal!
Whatta deal!
by Giordoma'am March 05, 2016
by MiraculourLanaAdrianette April 29, 2021