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The slang meaning is, to Cut a person or thing
"I'll Slice Your Neck!"
slice by 187 April 6, 2003
similar to cool or slammin but involves a higher degree...do NOT use this word unless you can fully handle it
I'm not slice enough to wear them for sport
slice by ChandelliMartini!! March 24, 2005
to take a long, smooth hit (preferably weed) from a bong/vape/etc
"yo i just took a huge slice"

"that was a ridiculous slice"
slice by toked prophet October 15, 2009

Kimbo Slice

v:To go so gorilla shit on a chicks' vagina that she just fucking explodes.
"I Kimbo Sliced a bitch last night."

"Damn, I would so Kimbo Slice that shit."
Kimbo Slice by Jeremiah R. June 16, 2008
Nickname (M/F) for a true redhead. If collar and cuffs match then pubes will resemble a slice of pizza.
"Yo, Slice, how's your trip?"
slice by sKiDz June 7, 2004
Shortened down way of calling someone a slice of shit.
A slice of shit is someone who is such a fucker that they must indeed have spawned from a slice of shit most foul.
Boy, that Ruma? what a fuckin' slice!

Charlie's a little bitch and certainly the biggest slice I ever did see!

Chris, you are the master of all things slice!
Slice by seanyc123 June 8, 2007