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Tweek

When a girl plays with her Vag for pleasure or to tease men
My hoe girl friend was caught tweekin off at a party, all the guy seen her cookie
by Savoyo September 28, 2008
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Tweek

Can be a state of paranoia, Have to urge to hurt or kill somebody, Be Extremely mad (sometimes because of drugs or mental ilnesses)
by Mike AKA TweeK December 14, 2008
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tweek

Generally used as a verb to refer to what a DJ does to the knobs on the mixer.
Did you see that DJ tweek the knobs?
Tweekin' the knobs!
by katze April 19, 2005
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Tweek-a-leek

Similiar to a "freek a leek", this kind of women also engages in sexual acts for fun, however, is driven into a deviant frenzy fueled by the drug "meth" and hence the "tweek" is incorporated.
"Damn yo, we was out in Riverside partying with some of my cousin's homies, next thing you know these dudes start racking glass and these straight up tweek-a-leeks was all up on me.."
by j.sleaz March 18, 2009
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Tweek

A mad individual who can cause pain to himself and not give a damn. the spawn of god and satan.

Will act as below:
Runs around fields on cold night, in only his underwear, smoking and screaming "I rape chickens". sleep talks about foursoms, chickens, wanting sausages, and aaarrghffejwfbisduf!!
by Ernie October 15, 2004
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Tweek

to pinch or flick
I tweeked her nipple and she tweeked my clit with her tongue.
by Junebug January 13, 2004
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tweek

something that looks strange or is very cool
dude that shit is tweek!
by steakman1 February 12, 2007
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