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fo shizzle my nizzo 

The breakdown to this is the expressor to the expressee: shizzle my nizzo! This means putting action upon any object. Shizzle is the verb and Nizzo is the object of the verb. The expressor is asking the expressee to "do something to something"! Whatever it is and to what is up for purely speculative interpretation and depends on the linguistic conditions and the situational environment of the moment.
Lord girlfriend, I haven't seen you for so long. Come over here and "shizzle my nizzo"!
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fo shizzle my nizzo 

"you wanna run a train on this whoa?"
"fo shizzle my nizzo!"
fo shizzle my nizzo by ryan September 15, 2003

fo shizzle my nizzo 

Generally means that the person saying it, is a twat
Hey! fo shizzle my nizzo biotch mo fo uhhmmmmmmmm. sup girlfriend?
fo shizzle my nizzo by pea fan September 15, 2003

fo shizzle my nizzo 

means "for sure my brother" or "for sure my friend"
When asked if the party was good...
"fo shizzle my nizzo!"
fo shizzle my nizzo by Kristy September 16, 2003

fo shizzle my nizzo 

for sure my brother i.e. the affirmative, yes , thats right
Wanna hit this 40?
For shizzle my nizzle!
fo shizzle my nizzo by q September 9, 2003

fo shizzle my nizzo 

fo shizzle my nizzo by Sean September 17, 2003

fo shizzle my nizzo 

I have a long nizzo.
fo shizzle my nizzo by sukebe January 27, 2004