if you are meeting someone for the first time safe is usually used by making a closed fist with your hand and touching the other persons fist to greet them.
Having high quality of character so as not to be the type of (most often guy) who will fuck you over through association; Not a shmuck. (See Fuck Over)
Who? Daniel? No, man. Don't tease her about him He's safe, so chill. No need to be startingfights.