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Knock, Knock Motherfucker 

When you are urinating when suddenly you need to violently shit. Then, you stop pissing and turn around, firmly pressing your puckered ass onto the seat and unloading an ungodly amount of assham into that poor, poor toilet.
Larry: "Damn, I thought you were taking a leak!"

Jim: "Yeah, sorry. I had a Knock, Knock Motherfucker moment."

Larry: "A what now?"

Die, motherfucker! 

An increasingly popular mass refrain in the United States, directed at the Insurrectionist in Chief, due to his unstoppable deranged determination to destroy democracy and deprive US citizens of everything they know and love about being an American.
Although it’s sad and horrible to have such a socially and spiritually unacceptable thought, many American patriots, simple humanists, and scholars cannot help but utter the words, or at least think, “Die, motherfucker!” when they consider the depth of depravity that exists in this singularly pathetic and deeply destructive human being.
Die, motherfucker! by Dr Bunnygirl November 28, 2023

Downedest mother fucker

(noun) Tried and true, faithful-to-the-end; unwaveringly loyal to the core; your #1 ally when the shit goes down and your cause may very well be a lost one.
I was worried about John going to that part of town, but then I learned Nikki was with him. Nikki considers John a friend and is the downedest mother fucker I know. By me learning that I brushed my worries to the side. Nikki would watch out for John and put John's well being above his own .

dumb mother fucker 

Beto O'rourke Threatened to take AR 15's from lawful owners. Beto is from TX, where it is legal to protect personal property with Deadly force.

Beto is a dumb mother fucker!
person a: Beto just proposed buying back assault weapons.
person b: How can they buy back what they never owned?
person a: Beto is a dumb mother fucker!
dumb mother fucker by Dead Pool Fan September 16, 2019

Disingenuous Dense Mother Fucker 

A man who cannot tie his shoes.
Disingenuous Dense Mother Fucker: a man who can not tie his shoes and can fail you a speed-run.

caw caw motherfuckers 

A phrase commonly used by bird bitches before shit gets real