Duff

The brand of beer that Homer drinks in the Simpsons.

Duffman approves this definition

by kunemvu February 23, 2020

Duff

The ugly friend you bring out with you.

Ian is not a Duff

by QuinnIsAJag January 19, 2020

Duff

Dumb, Ugly, Fat, friend

Oh my gosh she is such a duff..

by gamerpeeps500 August 23, 2021

duff

designated, ugly, fat friend

That fat bitch over there, with those other girls, is so ugly... she is such a duff.

by Liz O'nya August 15, 2016

Duff Brain

An Über fluky dudely/dudette, that drinks to the point of being a problem for others. He/she somehow gets girls/dudes even though they either have a pencil for a penis or the chesapeake bay tunnel for a SNATCH. Aswell as being a drinker, they have terrible hair cuts, and think that they rule every city they find their way into.

Can be used as a Noun or Verb.

Drinks of choice: Fortays (40's), Vodka in a 2 liter, or colt 45
Music: Bad Euro-trash House stuff
Permanent residence: Ocean City, MD or NJ

1. dude one: "Dude, why the fuck did we bring brent.... he is duff braining so hard tonight... it's funkin' ruining my night."

dude two: "I know, it's my bad, but you won't have to see him again till next summer."

2. dudette one: "Ugh, you are way to drunk Brittany, you are a funkin' duff brain and you even knew I wanted that kid..."

dudette two: "OMGEEZ WTF alls I was gonna do was willis with him all night."

by brew thru her August 29, 2012

Pulling a Duff

Sitting on your ass and not doing anything.

The dude was so hungover Duff didn’t lift a finger.... he was pulling a Duff

by Doepke April 23, 2021

DUFF

A term describing depressed, ugly, feminist females. DUFF for short.

"An ugly chick i know complained that i wasn't open minded enough about her genderless kitten, and that i was being sexist, and was also guilty of raping her."

"Oh she must be part of DUFF."

by mahaaham May 30, 2015