Duff!

Someone who does not give a shit that he is the leader.

Dude! Do something, don't be duff!

by TrexMike March 17, 2021

Duff

The brand of beer that Homer drinks in the Simpsons.

Duffman approves this definition

by kunemvu February 23, 2020

Duff

The ugly friend you bring out with you.

Ian is not a Duff

by QuinnIsAJag January 19, 2020

Side Duff

(1)When you are/are not in a relationship. and have a person you fuck on the side. Side duffs manly are just people who you don't really care about, but just only to fuck.

(2) Someone who likes/loves you a lot and buys you stuff and is always promised sex, but never get any in return.

(1) monica was Bill Clinton's Side Duff

by Pititfulfilth April 1, 2011

come up duff

A person who was a duff in their past and is now a hot glown up masterpiece

Guy 1: Damn heathers a come up duff!
Guy 2: Yah she used to be really ugly but now I really wanna date her

by Em's definitions August 14, 2017

Duff

Beer you wish you could have but never will.

I'm craving some duff right now bro.

by lemonberrypie August 4, 2017

duff

duff

Duff
Designated. Ugly. Fat. Friend
Ex. Britny is the duff in the group
Lisa and jen are hotties or the atravtive one and britney is ugly and fat compared to them
It can be guys (not alway ugly or fat) lets say they are freshmen and are like wingmen to upperclass men
*They are the ones who the girls go to ask if the jocks or alist guys in the group are single

The 2015 movie "Duff" is about a girl who is the duff in her group of friends at highschool who was unaware that she was the duff and was set oit to change it

"Duff " is not a positive thing to be called

by just a teen in 2k15 March 31, 2015