by pwoqowihshdh August 21, 2020

April 21 is the best day ever!
by SpecialKeg December 20, 2010

if you’re an omarito and you were born on this day that means you have a big fat fucking juicy thick mouth watering dick and that i want it all in me
by dodaphatass April 21, 2021

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.
He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.
by Jennica Starlight November 30, 2004

by Your savoury November 9, 2019

by Ya boy bray October 19, 2019

Paige: yo guess what day it is!!
Ashlynn: oh god what!?
Paige: it's December 21, it's national weed dayyyy!!!!
Ashlynn: oh god what!?
Paige: it's December 21, it's national weed dayyyy!!!!
by paigeroussel November 2, 2020
