zit zilla Share definition Flag A large and often fat person with so much acne they are unrecognizable as human. Ben: Omg dude did you see that zit zilla? Jeff: Yeah bro, you could pump oil from that thing. zit zilla by Bdub69 August 28, 2006 0 0 Get merch Get the zit zilla mug. Buy Now — $32.95 See more merch