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Nagasaki 

An atomic shit. The kind of shit that leaves the bathroom in a toxic, radioactive state for up to hours after the disaster.
Holy crap, Adam definitely dropped a Nagasaki in there. I almost threw up and I barely got past the bathroom door.”

“Bro, it’s bad enough that you dropped a Nagasaki in there. But for the love of God, can you please make sure there isn’t any fallout left in the toilet after you flush? Nobody needs to see that”
Nagasaki by NiLemonHeadass January 24, 2023
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dropping a nagasaki 

frankly this means taking a dump...but in reference to the bomb that the US dropped on the Japanese island of Nagasaki during World War II
Ed: (on the phone): Hey Joe whachu up to?

Joe: Hey Ed, im dropping a nagasaki right now can I call you back?

nagasake 

Created one fateful night on spring break, a nagasake is a bomb containing Bacardi 151, Jägermeister, sake and beer - a concoction so strong, only the bravest have ever kept it down. Legend has it, it's creator still hears the drunken babbling of the fallen to this very day.
Everyone was amazed at how well Nathan killed that nagasake, until he chundered everywhere.
nagasake by KeepOnMuvin March 16, 2015

Nagasaki 

A Japanese city founded by the Portuguese in the late 16th century and unfounded by America in 1945.
Dude:Hey America, what happened to Nagasaki?
America: I did a little renovation.
Nagasaki by Pipinghotboi November 11, 2020

The Nagasaki

As you are banging your girl from the rear you tell her you would like a blowjob. As she stands to change positions you throw a Stone Cold Stunner on her knocking her out. You then proceed to trash her place by flipping over furniture and breaking anything you can before exiting. When she awakes it will look and feel like a bomb went off.
Jenny wanted to try something different so I let her have The Nagasaki.

Nagasaki 

an alcoholic drink...japanese beer with a shot glass of saki dropped in.
Nagasaki by ShoeWe January 24, 2008

Nagasaki 

Excessively spicy or burnt food. Implied reference to the 1945 atomic bombing of this unfortunate Japanese city.
They're offering Nagasaki Chicken in the canteen again today.

I'd suggest you pass on the Nagasaki Sauce, it's lethal.
Nagasaki by ud40 February 24, 2005