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C. diff

aka clostridium difficile

A species of Gram-positive bacteria of the genus Clostridium that causes diarrhea and other intestinal disease when competing bacteria are wiped out by antibiotics.
I took Cipro for an ear infection and now I have C. diff. Should I sue the doctor or the pharmaceutical company?
by advocate4health April 4, 2010
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Jett Diff

The differentiation in the ability to play the Agent, Jett, In Riot's Valorant.
-"How did she win that fight?!"

-"Jett Diff"
by Tactical Waffles June 21, 2021
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Diff breather

The lower opening of the digestive tract. It is associated with the anal sphincter and lies in the cleft between the buttocks, through which fecal matter is extruded.
Hey Toby, remember that time when you caught Ryan smashing your mum in her diff breather.
by MickyT91 November 5, 2018
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robbie diff

an individual who disregards all social norms and behaviours that are considered by the majority to be acceptable, respectable or appropriate; while demonstrating an exceptional tolerance to alcohol consumption and educating the masses on the numerous and unique ways that the C-Bomb can be inserted into a conversation
by james.g.j.brown May 21, 2011
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diff master

1. A person with way too many problems.
Reko is a diff master because he thinks his facebook account got deleted. It's always something new with that kid.
by JACit April 25, 2006
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SHIT THE DIFF

When something or somebody has an accident or breaks something or breaks down mentally and/or physically.
Jim has finally shit the diff and is in hospital in recovery
by EXLER December 26, 2015
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jiffy diff

When a certain person masterbates to a anime doll
Aw mom how many times did I tell you to knock before you walk in! I was doing the jiffy diff
by Jiffydiffer January 29, 2018
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