s 

It's short for the Spanish word for "Gangster" (can’t recall the word, but I starts with an S). However, it sounds like "ese" when pronounced. Same thing if you said "G". This means "What's up G" and "What's up S (ese)" both mean the same thing, namely, “What's up gangster”.

Homie 1: What's up S (ese)?
Homie 2: Nothing G.

s by bobie January 14, 2007

s 

security on the block

Man, we gonna have to control this block, I need some peeps up on "s" to watch out for the poleece.

s by JayByrd July 3, 2006

S 

apparantly a person?
some guy who hijacks projects and generally just seems to be...
there.

That dude over there? S? He's... Been writing something on his phone for like an hour now.

S by not s November 18, 2018

S 

IS A BITCH I HATE S SMMMMMMM (aimed)

s is a hoe...:)

S by bolipop May 24, 2022

S 

A symbol of an S was usually drawn out in middle school or late elementary. Usually the ones who drew it were "artists" in the class but mainly they were selfish faggots who didn't want you to know what the S meant because they didn't even know what it meant. Infact the S symbol has no origin, no one knows about it but we've apparently been drawing it for decades.

What does the S your drawing mean? It's a secret!

S by Don't use your real name.. July 2, 2018

S 

S

S

S by Mr.Swipez1 March 22, 2019

s 

A suffix used to shorten words: probs, totes, supes, prets -- that is, probably, totally, super, and pretty

doo: stop saying prets
me: probs not, I supes love saying prets

s by roxuay September 15, 2017