duff

The leftover remnants of meth after smoking. Or small crystals of crappy meth that can be found on tables, etc, in a meth user's home.

We opened to basement door and told Jeff's uncle it was time to go. He screamed "Do you want me to do this F*kking Duff, or what!!!!??" while pounding a table.

by StinkyPP August 8, 2008

Duff

The asshole

That man takes it up the duff

by yogybear June 2, 2009

duff

Dumb, Ugly, Fat, Fuck.......... every girl has a friend like this.

that girl is friends with that DUFF chick

by Tin973 November 10, 2006

Duff

Designated Ugly Fat Friend

I got drunk last night and slept with the Duff.

by zeee! January 7, 2009

duff

"designated ugly friend"

an ugly poor girl you use to laugh at. She has such a scummy pathetic life and drives a 2 dollar pos. Her face is ugly too. Her family is fucked in the head and she makes you feel better about yourself. Though you don't have to, she can make anyone feel better about herself since her life is such a piece of shit.

Boyfriend: don't call the duff tonight, she's too psycho to hang out with.

Girl: Don't worry, i won't, i don't hang with her anymore, it ruins me reputation.

by tawns02 December 9, 2008

Cassandra M. Duff

Sometimes a little strange, or even dangerous. Beautiful and shy none the less.

Warning: may charge like a bull.

"You pissed me off, so i charged your ass."

by Chris Ellis February 8, 2005

hilary duff

Slang for powder cocaine. Originated from the term "white girl" used by E-40 and other bay area rappers. Another nickname is Vana White...or you could use any famous white girl that is skinny enough to snort like a line of coke.

I dont want no p*ssy, I dont want no head.... But you can get a sack of that purple stuff, some gin and a bag of that Hilary Duff! -Messy Marv

by sleezy415 October 10, 2010